PDE & PK Def Testing
Health testing is very important, and so is the transparency of health testing. Please find our results of the PDE and PK Def. for our dogs. Please keep in mind PDE can be clear by parentage. Both parents would have to be N/N for this.
Pug Dog Encephalitis (PDE) DNA Testing
Pug Dog Encephalitis (PDE), also known as necrotizing meningoencephalitis (NME), is an inherited brain disease affecting pug dogs. It is described as an aggressive and fatal inflammatory disease of the central nervous system.
Pug PK Deficiency DNA Testing Results
Pyruvate kinase deficiency (pug type) is an inherited metabolic disease affecting pugs. Affected dogs have insufficient activity of the pyruvate kinase Enzyme, which breaks down glycogen for energy. Deficiency of this enzyme results primarily in easily damaged red blood cells (hemolysis). Affected dogs typically present between 4 months and 2 year of age with pale gums from decreased numbers of red blood cells (Anemia) and lethargy or exercise intolerance. Clinical findings during a veterinary exam include severe anemia, hardening of the bones, and an enlarged spleen and liver. While dogs can live for several years with this disease, they typically die from severe anemia or liver failure between 5 to 9 years of age.
